Exon 2 was flanked by loxP sites. An FRT-flanked PGK-neomycin selection cassette was inserted between exon 2 and the second loxP site. Flp-mediated recombination removed the selection cassette. (J:236556)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count