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A targeting vector containing (in order from 5' to 3') encephalomyocarditis virus IRES, tandem dimer (td) Tomato, T2A self-cleaving peptide from Thosea asigna virus, Cre recombinase fused to the estrogen receptor ligand binding domain (ER), bovine growth hormone poly(A), and a frt-flanked neomycin resistance cassette was inserted in exon 8 downstream of the endogenous stop codon. The neomycin selection cassette was excised in male mice by crossing to FLP1 expressing female. (J:282429)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
