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EN
The ICR (2.4 kb BglII fragment with chromatin insulation, promoter silencing and imprinting (differential methylation) function) between the Igf2 and H19 genes was replaced with a loxP site flanked neomycin resistance gene cassette and a 2.4 kb sequence containing two copies of the chicken beta globin chromatin insulator ((ChbetaGI)2). The neo cassette was removed through subsequent cre-mediated recombination. (J:308869)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
