A vector, which contains (5' to 3') a splice acceptor, floxed neo/stop cassette and sequence encoding nuclear localized lacZ was inserted immediately was inserted into the locus via homologous recombination. The parental Gt(ROSA)26Sortm3Etz was crossed to cre deleter to remove the floxed neo/stop cassette. The b-galactosidase molecule active and expressed ubiquitously in all cells/tissues. (J:278250)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count