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The transgene contains the human genomic FUS locus from a 225 kb BAC, RP11-388M20 (BACPAC resource centre, Childrens Hospital Oakland Research Institute) with loxP sites, and an mCherry reporter gene. The exon 15 mutation (c. 1574C-T) was inserted separately by site-directed mutagenesis. Lines 1 and 3 were generated. (J:82809)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
