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Genomic fragments containing mouse Igh 3' regulatory regions hs3a, hs1,2, hs3b and hs4 were placed downstream (in their endogenous order) of a mouse Myc gene cassette (comprising genomic sequence for Myc promoters P1 and P2 and all exons and introns). The entire construct was flanked by chicken beta globin HS4 insulator sequences to promote position independent and copy number dependent regulation of the inserted gene by the regulatory regions. (J:131646)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
