A targeting vector introduced an IRES-CreERT2 cassette along with an FRT flanked PGKneo cassette into the 3' untranslated region of the Hic1 gene. Male chimeras were subsequently bred to Flippase-expressing mice to delete the PGK-neo cassette. (J:292396)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count