This insertion contains (in order) a CAGGS promoter, FRT-flanked neo cassette with 2 poly-adenylation sequences, floxed EGFP followed by 5 poly-adenylation sequences and a lacZ gene with a nuclear localization sequence. Parental Gt(ROSA)26Sortm5(CAG-EGFP,-lacZ)Dym was crossed to cre deleter mice to remove EGFP-STOP cassette. Nuclear-lacZ expression results from FLP- mediated recombination. (J:290856)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
Insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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