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A targeting vector containing a 3' FRT flanked neo cassette and P2A-GFP-CreERT2 cassette was inserted to exon 38 of the Lrp4 gene via homologous recombination in C57BL/6J-derived embryonic stem cells. Heterozygous animals were crossed subsequently to FLP recombinase expressing mice to remove the FRT site flanked PGK-neo cassette. (J:291055)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
