The targeting construct inserted a floxed neomycin resistance cassette inserted downstream of the C beta2 exon and modified the third Runx1-binding site within the Ebeta enhancer (TGCCACA to TTGGACA). (J:274549)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count