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A cassette encoding for a fusion protein consisting of the Internal Ribosome Entry Site (IRES), eGFP, Cre and human-modified Oestrogen Receptor (ERT2) (IGCE) was linked to a Frt-flanked neomycin (NEO) encoding cassette and inserted downstream of the translation stop codon in the mouse Il17a gene by targetted homologous recombination in ES cells. Germline transmitted mice were bred with germline Flippase expressing transgenic mice to remove the neomycin gene. (J:224098)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
