Alanine codon 155 (GCC) in exon 5 was changed to a stop codon (TGA) (p.A155*) using an sgRNA (targeting GGAAGATATGTAATCAGGCTCTT) and an ssODN template with CRISPR/Cas9 technology. (J:308301)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
mixed
Endonuclease-mediated
Nucleotide substitutions
--
1
37
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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