The endogenous exon 28 was replaced with the human exon 28. The loxP site flanked neomycin resistance gene cassette that was inserted into intron 28 was removed through subsequent Cre-mediated recombination. (J:270490)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count