An 81 kb genomic segment encoding Sprr2a1, Sprr2a2, and Sprr2a3 is deleted using CRISPR/Cas9 methodologies (gRNAs: GTGTAGAAAAAAGGATCGGTGGG (upstream), and ATTATCAGCGGTGTACTGCCAGG (downstream); GRCm38.p6: 92,210,732-92,291,813). (J:314159)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count