An M2rtTA/IRES, loxP flanked GFP, polyA, and an FRT-flanked neomycin cassette were introduced immediately after the ATG codon in exon 1 of the mouse Mecom gene via homologous recombination in embryonic stem (ES) cells. The resultant mice were crossed with Flp-expressing mice to remove the selection cassette. (J:292941)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count