Anxa10^{Tg(EEF1A1-lacZ)78-8Tyama}

Using a lacZ transgene driven by the human EEF1A1/EF1alpha promoter, a transgenic mouse line (line 78-8) was established by the transgene injection into 1-cell embryos. The genomic sequencing of the transgenic mouse revealed that both Spock3 and Anxa10 were disrupted simultaneously on chromosome 8 by the transgene insertions, resulting in double-null mutations of these genes. (J:308070)