The targeting construct replaced the endogenous gene with a modified human gene in which a lacZ reporter gene and neomycin resistance cassette replaced 16 bp in exon 12, which encodes the catalytic domain disrupting it. (J:307334)
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The targeting construct replaced the endogenous gene with a modified human gene in which a lacZ reporter gene and neomycin resistance cassette replaced 16 bp in exon 12, which encodes the catalytic domain disrupting it. (J:307334)