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CRISPR-targeting deleted the constitutive promoter, exon 1B, and a possible alternative exon 1C required for the transcription of the p110 isoform. Expression of isoform p150 is not altered. Two lines were generated with almost identical mutations. The two lines (Adarem3Osb and Adarem4Osb) were combined (indicated by the pound symbol #). (J:306164)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
