The targeting construct flanked exon 11 with loxP sites. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted into intron 11. (J:306165)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count