The transgene based on murine BAC clone (RP23-343C17) containing the sequence between the proglucagon start codon in exon 2 and stop codon in exon 6 was used to express iCreERT2 under the control of the proglucagon promoter. Initially, two transgenic lines 9 and 17 were established both with an estimated transgene copy number of one. The initial characterization did not reveal any differences. (J:295333)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x CBA
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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