Cre recombinase replaced exons 2-4 of the Epo gene in a BAC clone (Epo-60K/BAC). This transgene expresses cre recombinase under the control of the Epo regulatory elements. Three lines were established, and line 44 was crossed to reporter animals and analyzed further. (J:231255)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count