The transgene contains the BAC RP23-128D19 with the cre recombinase fusion to the modified estrogen receptor (ERT2) inserted downstream of the translation initiation codon. Five transgenic founder lines were generated with one (line 151) showing specific cre activity in the lymphatic valve was established for further studies. (J:308453)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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