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By homologous recombination in embryonic stem cells (ES), two loxP sites and a neo cassette were introduced flanking the exon 2, one at 212 bp upstream of exon 2 and another at 53 bp downstream of the exon 2 after the Neomycin resistance cassette, which was flanked by two FRT sites. The floxed exon 2 and neo cassette were removed by breeding with a cre-deleter constituting a Cplx1 null allele. (J:298868)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
