A lacZ-neo cassette flanked by loxP and rox sites at the 5' and 3' ends, respectively, was inserted into the intron between exons 6a and 6b. Another rox site was inserted upstream of exon 6a and another loxP site downstream of exon 6b so that dre/rox recombination can remove exon 6a and the lacZ-neo cassette, and cre/loxP recombination can remove exon 6b and the lacZ-neo cassette. (J:293382)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
Insertion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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