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By homologous recombination in ES cells, cre-SV40 expression cassette and the PGK promoter (PGK) followed by a neomycin-resistant gene (Neo) flanked by FRT was inserted at the ATG site of exon 1 of Nox3 on chromosome 17. The founder mice were crossed with CAG-FLP mice to remove the Neo cassette. This is a null allele. (J:306032)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
