Exon 5 was flanked by loxP sites. An FRT-flanked neomycin resistance cassette was inserted 1128 bp upstream of exon 5. Flp-mediated recombination removed the selection cassette, leaving exon 5 floxed. (J:288182)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count