CRISPR/Cas9 endonuclease-mediated genome editing is used to delete exons 3-7 using single stranded guide RNAs (TCAAGCCTGACAAGTACTGA and ATCAAGCCTGACAAGTACTG upstream of exon 3 and CCGTGATACCACCAGAAGGC and GGCTCCGTGATACCACCAGA downstream of exon 7). (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count