A loxP site was inserted into intron 5 and a second loxP site into intron 7. The loxP sites are approximately 1.3 kb apart and flank RING domain coding exons 6-7. The FRT site flanked neomycin resistance gene cassette that was also inserted, was removed through subsequent flp-mediated recombination. (J:236636)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count