The targeting vector contains a loxP-flanked neomycin cassette introduced to intron 2 and a loxP site in intron 3. Cre-mediated recombination removed the floxed neo cassette leaving exon 3 floxed. (J:245106)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count