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The tetO tetracycline responsive element followed by cDNA sequence coding for the zinc and ring finger 3 extracellular domain were inserted into exon 1 of the locus. The CAG promoter followed by the rtTA16 transactivator cDNA was inserted into intron 1 in the reverse transcriptional direction. This allele expresses the Znrf3 sequence in the presence of doxycycline. (J:236636)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
