The targeting construct contains a T2A-sfGFP-icre/ERT2-FRT-neo-FRT cassette, which replaces the stop codon just before the 3' untranslated region. The GFP fluorescence is not detectable because the GFP fluorescence is dim. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:286603)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count