A targeting vector was designed to replace the entire coding region of the prepro-Qrfp sequence in exon 2 of the Qrfp gene with iCre and a pgk-Neo cassette so that the endogenous Qrfp promoter drives the expression of iCre. The Pgk-Neo cassette was deleted by crossing the mice with FLP66 mice. It is a knock-in, knock-out allele. (J:294111)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
Insertion, Intragenic deletion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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