The transgene comprises the MHC class II (I-Ab)-restricted TCR specific for a peptide derived from the glycoprotein (G) of vesicular stomatitis virus serotype Indiana (VSV-IND), derived from the Vb2+ T cell hybridoma 31.2.10 Tcrb gene (leader, Vb2, Db1.1, Jb2.1, Cb2) . The TCR sequence was preceded by the H2-Kb promoter and followed by beta globin intron 2, poly(A) signal sequences and an Igh enhancer. (J:307526)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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