CRISPR/cas9 endonuclease-mediated genome editing is used to create a 95 base pairs (131-225, Gm16286, UniProt Q9CQX6 ) deletion. The mutation creates a frameshift resulting in a termination codon at amino acid 67. (J:308825)
Basic Information
(C57BL/6 x DBA/2)F1 x C57BL/6J
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count