The transgene consists of a myristoylation/palmitoylation site-attached GFP (myrGFP) inserted into the start codon located in the exon 2 of the Pvalb gene so that it is under the control of the mouse Pvalb promoter. The modified BAC transgene construct DNA was purified and linearized then injected into pronuclei of B6D2F1 mouse zygotes. Three founder lines I, II, III were generated. Line II was used for the study. (J:187049)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6D2F1
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Insertion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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