Tg(Myh6-Akt1*)6445Gcon

This transgene insert contains the following elements: mouse cardiac muscle myosin heavy polypeptide 6 alpha promoter sequence to drive the heart-specific expression of a constitutively active mutated form of the mouse thymoma viral proto-oncogene 1 cDNA where codon 40 was changed from glutamic acid to lysine (p.E40K) through a G-to-A point mutation (c.118G>A), and SV40 intron and poly(A) signal sequences. (J:258598)