Using the CRISPR/Cas9 technology, the line was generated by inserting a cDNA encoding cre/ERT2 recombinase into the translational stop codon of the Col1a2 gene, following endogenous Col1a2 by the self-cleaving peptide 2A sequence. (J:248362)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
Insertion
--
1
18
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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