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The parental Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze strain containing a pair of FRT sites flanking the reporter, in addition to the flox-stop cassette placed between the CAG promoter and ZsGreen was mutated to eliminate the downstream FRT site with Crispr-CAS9aided targeting. The microinjection of the guide RNA and CAS9 constructs into fertilized embryos generated the modified alleles, named R26Z10, was established and used in the study. (J:297537)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
