A floxed STOP cassette and a mutated invariant chain molecule Cd74 cDNA in which the sequence encoding the CLIP domain was replaced with the immunodominant GP61-80 peptide sequence of LCMV were inserted into the locus. Expression of the fusion product is only achieved following cre mediated recombination. (J:306965)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count