This transgene construct contains the following elements: the CAG promoter, a loxP site, the mouse eukaryotic translation initiation factor 2 subunit 1 alpha cDNA, a second loxP site, the EGFP fluorescent marker gene, and bovine globin poly(A) signal sequences. Founder 11 has a single copy of the transgene. The transgene will express Eif2s1 as is, but EGFP after cre-mediated excision of the Eif2s1 sequence. (J:151620)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J x SJL
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Insertion
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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