The targeting vector inserted into the Gt(ROSA)26Sor locus a CAG promoter, floxed STOP cassette (with stop codons in all 3 reading frames), FLAG-tagged cas9, P2A, tdTomato reporter, WPRE and polyadenylation sequences followed by FRT flanked neomycin resistance cassette. (J:293217)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count