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CRISPR/Cas9 technology inserted a hemagglutinin tag sequence followed by four stop codons (HA-Stop sequence) 3' of the four initial amino acids (EFCY) after the last transmembrane helix. This results in the truncation of the entire cytoplasmic tail after the fourth amino acid after the last transmembrane helix. Western blot analysis confirmed the absence of protein containing the cytoplasmic tail domain in homozygotes. (J:306675)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
