An IRES-CreERT2-polyA-SDA-Neo-SDA cassette was inserted into Xcm1 site within the exon 5, which encodes part of the T box domain resulting in a functionally null allele. The neo cassette was self-excised in the ES cells. (J:303592)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count