The targeting vector inserted into intron 5 a an FRT site, splice acceptor, lacZ reporter gene, loxP site, neomycin resistance cassette, FRT site, and loxP site. An additional loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the reporter/selection cassette and left exon 5 floxed. (J:306502)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count