The targeting construct inserted an FRT-flanked beta-geo cassette with a 3' loxP site upstream of exon 2. An additional loxP site was inserted downstream of exon 3. (J:292199)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count