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An improved cre (icre) gene was inserted downstream of the prostate-specific composite promoter that consists of two androgen response elements (ARR2) and mouse probasin (Pbsn) promoter. A total of 94 founders was generated. Line 58 with the detectable icre mRNA expression by RTPCR in the prostate was kept for further analyses. The expression of icre was mostly limited to the prostate gland with a trace expression in the seminal vesicle. (J:304912)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
