A loxP site and FRT-flanked neomycin selection cassette were inserted into the third intron and a second loxP site was inserted in intron 4. Flp-mediated recombination removed the selection cassette and left exon 4 floxed. (J:306663)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count