A FlpO-lox2722-PGK-Neo-lox2722 cassette was used to replace the coding sequence of the mouse Atoh1 gene, leaving the transcriptional start site intact by homologous recombination in ES cells. The PGK-neo cassette was removed by crossing with cre expressing mouse. (J:268187)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion, Intragenic deletion
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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