The T2A-iCre sequence and neo selection cassette were inserted in-frame to the 3-end of the Cd19 coding sequence immediately upstream of the stop codon using CRISPR/Cas9-mediated homologous recombination technology. Flp-mediated recombination removed the selection cassette. (J:304919)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count