An EGFP gene with poly(A) signal sequence was inserted between the 2nd and 3rd nucleotide of exon 2 of the Il11 gene on BAC clone RP23-285B12 to create an Il11 promoter-driven Il11/EGFP fusion gene coding for the first three Il11 amino-acids followed by the EGFP peptide. The modified BAC was injected into oocytes together with sperm through Intracytoplasmic sperm injection (ICSI). (J:306086)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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